This search function provides links to outputs produced by NIHR Innovation Observatory. These are briefing notes or reports on new or repurposed technologies. This search will not return all technologies currently in development as these outputs are produced as required for our stakeholders.

Innovation Observatory > Reports > Anaesthetics, Pain Relief and ITU



December 2017

Neridronic Acid (Nerixia) for Complex Regional Pain Syndrome

Currently there are no approved treatments for CRPS. Neridronic acid administered by injection is currently being developed to treat CRPS and early results indicate that it has the possibility to control the condition. If approved neridronic acid will be a potential new treatment for CRPS.


February 2017

Mirogabalin for pain due to fibromyalgia

Mirogabalin is a new drug to treat pain associated with fibromyalgia. Fibromyalgia is a long-term condition that causes pain all over the body. Mirogabalin is taken by mouth once a day at bedtime. If licensed, mirogabalin may offer patients with fibromyalgia an additional treatment option.


September 2016

XG 102 for post-operative inflammation and pain following cataract surgery

XG 102 is a new drug injected into the eye to treat pain and inflammation in people who have had a cataract operation. A cataract occurs when the lens in the eye becomes cloudy causing blurred vision. Cataracts are very common and usually affect those over the age of 65 years. More than 300,000 cataract …


August 2016

Tetrodotoxin for moderate to severe, inadequately controlled cancer-related pain

Cancer-related pain can arise from both ongoing tissue damage and treatments such as surgery or radiotherapy. Many patients use opioid-based pain killers to manage cancer-related pain but often they do not have complete pain relief. Tetrodotoxin is a new drug that blocks pain transmission. It is reported to be a well-tolerated, more potent analgesic than …


May 2016

AXS 02 (zoledronic acid) for type I complex regional pain syndrome

Complex regional pain syndrome is a painful condition that can occur in an arm or leg after a broken bone, operation or other injury. The cause of this condition is not understood, and there is currently no cure for complex regional pain syndrome. AXS 02 is a new drug for complex regional pain syndrome in …


April 2016

High definition transcranial direct current stimulation for the treatment of fibromyalgia pain

High definition transcranial direct current stimulation (HD-tDCS) is a device to treat the muscle pain people get with fibromyalgia, where the usual pain killing treatment has not worked. Fibromyalgia is a relatively common muscle condition, the specific cause for which is currently not known. The technology consists of electrical conductors on a cap through which …


March 2016

Methoxyflurane (Penthrox) for emergency relief of moderate to severe pain

Acute pain is a type of pain that typically does not last longer than 6 months and stops when its underlying cause has been treated or has healed. It is commonly associated with broken bones, burns, pain after surgery or medical conditions such as heart attacks. Methoxyflurane is a new drug for the emergency treatment …


December 2015

ivWatch Model 400 patient monitor for continuous monitoring of IV sites

The ivWatch Model 400 patient monitor helps doctors and nurses find out whether a drip in the vein is leaking into the surrounding tissue. If this happens, it can cause pain, infection, tissue damage and loss of limb. The ivWatch system contains a patient monitor, a light, and a single-use container that secures the light …


November 2013

ATI™ Neurostimulation System for cluster headache

The ATI™ Neurostimulation System, developed by Autonomic Technologies Inc, is a rechargeable, implantable neuro-stimulator of the sphenopalatine ganglion, designed to relieve the acute pain of cluster headache and to reduce the frequency of cluster headache attacks.


May 2013

Glysure intravascular continuous glucose monitoring system for glycaemic control in intensive care

The Glysure intravascular continuous glucose monitoring system is designed for glycaemic control in patients who are in intensive care.

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